Weed is a Depressant, not a Stimulant

In medicine, depressant is used to describe drugs that reduce or relax bodily functions. It works by lowering the neurotransmission levels which represses certain functions and senses, this is why you feel less pain or arousal on depressants.

Weed strains have many effects typical of depressants such as muscle relaxation, tiredness, sedation, decreased alertness.

Weed is a complex plant, with major compounds such as tetrahydrocannabinol and cannabidiol, which have opposing effects. Tetrahydrocannabinol is one of at least 113 cannabinoids identified in weed.

THC is the principal psychoactive constituent of cannabis. The discovery of its compounds has led to the further discovery of an important neurotransmitter system called the endocannabinoid system. This system is widely distributed in the brain and in the body and is considered to be responsible for numerous significant functions.

Can Marijuana act like an Anti-Depressant?

While marijuana is categorized as a depressant, many Sativa, Indica, and Hybrid strains have anti-depressant properties, as well as many other health benefits. It can also depend on whether you buy CBD oil or THC to consume when feeling the different effects.


Tetrahydrocannabinol is one of at least 113 cannabinoids identified in weed.  The THC Tetrahydrocannabinol works to reduce or relax bodily functions. Weed lowers the neurotransmission levels which represses certain functions and senses. The level of a depressant on an individual depends on a wide variety of factors.

The depressant effects of weed include:

  • Deep Muscle Relaxation and Muscle Tension Release.
  • Sleepiness, Sedation, Decreased Alertness
  • Perception Alteration
  • Dilated Eyes
  • A Feeling Of Relaxation
  • Faster Heart Rate
  • The Sensation That Time Is Passing More Slowly
  • A Greater Sense of Hearing, Taste, Touch, and Smell.

Weed can also be classified as a depressant, a hallucinogen, a psychedelic, or as a drug that causes an altered state of consciousness with mild euphoria, relaxation, perceptual alterations, and enhanced sensory experiences. This topic will be for another post.

Weed strains create these effects by disrupting the interaction of nerve cells with the neurotransmitter serotonin. Distributed throughout the brain and spinal cord, the serotonin system is involved in the control of behavioral, perceptual, and regulatory systems.


Weed strains with various levels of THC such as Cheese Weed Strain, Super Lemon Haze, Bubblegum and Holy Grail will deliver a wide variety of depressant to the imbiber. The method of intake (smoke, dab, eat) will affect the level of depressant. Although your mileage will vary there are certain depressant effects that are pretty much a guarantee.



Following the intake of the weed strain, the THC Tetrahydrocannabinol kicks in sensory perceptions will be altered. Familiar faces and objects may appear unfamiliar or strange. This can result in great amusement for the persons who are high. Colours may appear particularly vibrant; aesthetic appreciation can be enhanced; and the mood of the individual can be projected onto everything around them.

Hearing and taste are often the sensory experiences most strongly affected by weed. People who have used weed will often report a greater appreciation of music, and may spend the entire experience listening to music and doing little else. Enhancement of the sense of taste can result in a specific type of binge eating called “the munchies,” in which larger amounts of food may be consumed than normal.

After you inhale weed smoke, its chemicals zip throughout the body. THC is a very potent chemical compared to other psychoactive drugs. Once in your bloodstream, THC typically reaches the brain seconds after it is inhaled and begins to go to work.

Weed users often describe the experience of smoking the drug as initially relaxing and mellow, creating a feeling of haziness and light-headedness. Experiences will differ depending on the particular weed strain.  A Death Bubba Weed Strain high will be very different to a CBD Dream Weed Strain high.

The user’s eyes may dilate, causing colors to appear more intense, and other senses may be enhanced. The interaction of the THC with the brain is what causes these feelings. To understand how weed affects the brain, you need to know about the parts of the brain that are affected by THC.

Here are the basics:

  • Neurons are the cells that process information in the brain.
  • Chemicals called neurotransmitters allow neurons to communicate with each other.
  • Neurotransmitters fill the gap, or synapse, between two neurons and bind to protein receptors, which allow various functions in the brain and body to be turned on and off.
  • Some neurons have thousands of receptors that are specific to particular neurotransmitters.
  • THC will act as a depressant to mimic or block actions of neurotransmitters and interfere with normal functions.

Your brain has groups of cannabinoid receptors concentrated in several different places. These cannabinoid receptors can affect the following mental and physical activities:

  • Short-term memory
  • Coordination
  • Learning
  • Problem-solving

Cannabinoid receptors are activated by a neurotransmitter called anandamide. Like THC, anandamide is a cannabinoid, but one that your body makes. THC mimics the actions of anandamide, meaning that THC binds with cannabinoid receptors and activates neurons, which causes adverse effects on the mind and body.

High concentrations of cannabinoid receptors exist in the hippocampus, cerebellum and basal ganglia. The hippocampus sits within the temporal lobe and is important for short-term memory. When the THC binds with the cannabinoid receptors inside the hippocampus, it interferes with the recollection of recent events. THC also affects coordination, which the cerebellum controls. The basal ganglia direct unconscious muscle movements, which is another reason why motor coordination is impaired when under the influence of weed.

Weed strains such as Holy Grail, Kush, and Zombie Kush contain hundreds of chemicals. 109 of these chemicals of which fit into a category called cannabinoids [source: Mehmedic et al.]. THC, of course, is one of these cannabinoids, and it is the chemical most often associated with the effects that weed has on the brain.


Every time someone smokes, Dabs, or ingests weed the THC (tetrahydrocannabinol) and other chemicals enter the user’s body. The chemicals make their way through the bloodstream to the brain and then to the rest of the body. The most powerful chemical in weed is THC, which is primarily responsible for the depressant.